NCT06302192

Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study)

RED-AKI: Renal Doppler in Acute Kidney Injury. Capability of Intrarenal Venous Flow Doppler (IRVF) to Predict Acute Kidney Injury (AKI) in Critically Ill Patients With Acute Respiratory Distress Syndrome (ARDS)

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 164 (estimated)
• Sponsor: Policlinico Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a multicenter international observational prospective cohort study. The main questions it aims to answer are: * PRIMARY AIM: To describe the capability of IRVF demodulation at diagnosis of ARDS to predict development of AKI within 7 days from the ARDS onset * SECONDARY AIMS: A)Describe the capability of IRVF demodulation or pattern of IRVF (continuous, pulsatility, biphasic, monophasic) to predict development of AKI within 14 days from the ARDS onset. B) To describe the RD parameters and VexUS in the AKI and no AKI patients over time. C) Describe the impact of invasive mechanical ventilation (IMV) on the intrarenal venous congestion and VexUS., D) Evaluation of effect of CRRT on IRVF pattern, VexUS and parameters. E) Describe the feasibility of renal doppler to assess IRVF in critically ill respiratory patients. F) Evaluate the incidence of AKD and CKD Participants will Adult patients with diagnosis of ARDS admitted to intensive care unit and undergoing invasive mechanical ventilation

Conditions

• Acute Kidney Injury
• ARDS, Human

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	ARDS+AKI	according to the clinical practice Reanl doppler and VeXUS score will be performed

Timeline

• Start date: 2024-04-01
• Primary completion: 2026-01-31
• Completion: 2026-06-30
• First posted: 2024-03-08
• Last updated: 2024-03-08