NCT06301555

Game-Based Digital Intervention for Relieving Depression and Anxiety Symptoms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 223 (actual)
• Sponsor: Adai Technology (Beijing) Co., Ltd. · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Objective: To collect preliminary data and assess the preliminary effectiveness of a game-based digital therapeutics (DTx) intervention for individuals with symptoms of anxiety and depression, and to investigate whether reinforcement learning (RL) can personalize the intervention and enhance effectiveness. Design: Randomized controlled trial with three arms. Setting: Internet-based recruitment and delivery of the intervention. Participants: 223 individuals with symptoms of anxiety and depression, aged between 18 and 50 years. Interventions: Participants were randomly assigned to one of three groups: game-based DTx with RL algorithm (RL algorithm group), game-based DTx without RL algorithm (no algorithm group), and a blank control group. Main Outcomes and Measures: The primary outcomes were reductions in symptoms of anxiety and depression, measured using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder 7-item scales. Response rates and rates of recovery, as well as the impact of demographic variables, were also examined.

Conditions

• Depression
• Anxiety

Interventions

Type	Name	Description
BEHAVIORAL	Reinforcement learning algorithm powered cognitive and behavioral intervention	Reinforcement learning algorithm powered cognitive and behavioral intervention
BEHAVIORAL	cognitive and behavioral intervention	cognitive and behavioral intervention

Timeline

• Start date: 2023-11-01
• Primary completion: 2024-01-01
• Completion: 2024-02-01
• First posted: 2024-03-08
• Last updated: 2024-03-08

Locations

1 site across 1 country: China