NCT06297200

Low-Intensity Focused Ultrasound and the Complex Patient

Investigations of Low-Intensity Focused Ultrasound Towards Treatment for the Complex Patient

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Virginia Polytechnic Institute and State University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Studying the effects of Low Intensity Focused Ultrasound (LIFU) on measures of pain, craving, and anxiety in a complex patient population.

Conditions

• Opioid Use Disorder
• Chronic Pain
• Anxiety Disorder

Interventions

Type	Name	Description
DEVICE	Low-Intensity Focused Ultrasound	A noninvasive brain stimulation device using low-intensity focused ultrasound (LIFU) - ultrasound will be used to test whether noninvasive brain stimulation can effect pain, craving, and anxiety.
DEVICE	Low-Intensity Focused Ultrasound - sham	A sham condition that will mimic the application of LIFU without actually administering any ultrasound to the brain.

Timeline

• Start date: 2024-12-04
• Primary completion: 2026-10-01
• Completion: 2026-10-01
• First posted: 2024-03-07
• Last updated: 2025-11-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study