NCT06293807

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine: A Short-term Clinical Response

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: The University of Texas Health Science Center at San Antonio · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Immediate post-suturing administration of either one of two dental anesthetic solutions or a placebo prior to dismissal.

Detailed description

This study seeks to evaluate the pain response following the administration of two anesthetic solutions just prior to patient dismissal from a surgical procedure: 2% Xylocaine with 1:100,000 epi and 0.5% Bupivicaine with 1:200,000 epi in comparison with 0.9% Normal Saline as a placebo. the study team will monitor pain response following these interventions at 4, 8, 12, 24, and 48 hours.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
DRUG	Xylocaine 2 % with 1:100,000 epinephrine	Local anesthetic used during dental procedures
DRUG	Bupivicaine 0.5% with 1:200,000 epinephrine	Local anesthetic used during dental procedures
OTHER	Placebo	0.9% Normal Saline solution used in place of local anesthetic

Timeline

• Start date: 2022-06-06
• Primary completion: 2023-04-16
• Completion: 2023-04-16
• First posted: 2024-03-05
• Last updated: 2024-03-08

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study