NCT06292221

Personalized Depression Treatment Supported by Mobile Sensor Analytics

Smart and Connected Health: Personalized Depression Treatment Supported by Mobile Sensor Analytics

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: UConn Health · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed. This present study seeks to develop and investigate an innovative digital system, DepWatch, that leverages mobile health technologies and machine learning tools to provide clinicians objective, accurate, and timely assessment of depression symptoms to assist with their clinical decision making process. Specifically, DepWatch collects sensory data passively from smartphones and wristbands, without any user interaction, and uses simple user-friendly interfaces to collect ecological momentary assessments (EMA), medication adherence and safety related data from patients. The collected data will be fed to machine learning models to be developed in the project to provide weekly assessment of patient symptom levels and predict the trajectory of treatment response over time. The assessment and prediction results are then presented using a graphic interface to clinicians to help them make critical treatment decisions. The main question the present clinical trial aims to answer are as follows: 1. Feasibility of the digital tool, DepWatch, to assist clinicians in depression treatment and inform their clinical decision process 2. Effectiveness of the digital tool, DepWatch, to improve depression treatment outcomes All study participants will carry the DepWatch app on their smartphones and wear a Fitbit provided by the study team during the study period. They will also complete brief questionnaires via the app at specific time intervals throughout the study period.

Conditions

• Depression

Interventions

Type	Name	Description
OTHER	A mobile Health (mHealth) tool called 'DepWatch'	The mobile Health (mHealth) tool 'DepWatch' developed by the study team consists of the DepWatch app that is uploaded on participant's smart phones with their consent and a Fitbit provided to the participants

Timeline

• Start date: 2024-04-04
• Primary completion: 2025-06-08
• Completion: 2025-06-08
• First posted: 2024-03-05
• Last updated: 2025-07-31

Locations

1 site across 1 country: United States