NCT06278792

Readily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart Failure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Ziekenhuis Oost-Limburg · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare physician-guided (SOC) versus nurse-led natriuresis-guided diuretic therapy in patients with acute decompensated heart failure (ADHF). The main questions it aims to answer are: * difference in natriuresis and diuresis * feasibility of the protocol. Participants will be asked to gather two 24 h urine collections. Researchers will compare SOC versus nurse-led diuretic titration to see if there is a difference in natriuresis after 48 hours.

Detailed description

The EASY-HF study was a single-centre, randomized, open-label study comparing standard of care (SOC) diuretic management at the treating physician's discretion with a nurse-led natriuresis-guided protocol in patients with ADHF. A bedside sensor was used to measure the urinary sodium content.The primary endpoint was total natriuresis after 48 hours. Secondary endpoints included safety profile and user-friendliness of both the protocol and the point-of-care sensor.

Conditions

• Acute Decompensated Heart Failure

Interventions

Type	Name	Description
PROCEDURE	Diuretic protocol	Nurse-led natriuresis-guided protocol based on a bedside urinary sodium result
PROCEDURE	Standard of Care	Diuretic therapy at the discretion of the physician

Timeline

• Start date: 2022-03-07
• Primary completion: 2023-07-12
• Completion: 2024-01-05
• First posted: 2024-02-26
• Last updated: 2024-02-26

Locations

1 site across 1 country: Belgium