NCT06243601

Effect of Aloe Vera Gel as an Intra Canal Medicament

Effect of Aloe Vera Gel as an Intra Canal Medicament in Patients With Asymptomatic Periapical Lesions.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Islamabad Medical and Dental College · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions. It will provide endodontists with scientific evidence regarding the beneficial use of AVG as an intracanal medicament owing to its superior antibacterial and analgesic properties as compared to routinely used commercial intra canal medicaments.

Detailed description

Objective: To evaluate the effect of aloe vera gel based on clinical signs and symptoms as an intracanal medicament in asymptomatic periapical lesions over a period of three weeks. Methodology: Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions in group A while in group B (control group) no intracanal medicament will be placed. Patients will be randomly divided into two groups by randomization in Statistical Package for Social Sciences software (SPSS v24.0). They will be recalled for one week and three week follow ups and in case of no clinical signs and symptoms endodontic procedure will be completed. Statistical analysis: Descriptive statistics will be used for reporting age. Frequencies and percentages will be calculated for categorical variables and intergroup comparison will be done by chi square test

Conditions

• Periapical Diseases

Interventions

Type	Name	Description
BIOLOGICAL	Aloe vera Gel	A fresh aloe vera (Aloe Barbadensis) leaf will be plucked from the plant. The leaf will be washed with normal saline, peeled with scalpel and the inner gel will be blended in a blender to convert it into a watery consistency. The solution will be stored in an autoclaved flask.

Timeline

• Start date: 2023-11-30
• Primary completion: 2024-08-20
• Completion: 2024-11-15
• First posted: 2024-02-06
• Last updated: 2025-05-21

Locations

1 site across 1 country: Pakistan