Trials / Recruiting
RecruitingNCT06216002
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Incidence of Residual Neuromuscular Blockade in Patients With Frailty Undergoing Gynecologic Cancer Surgery
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 622 (estimated)
- Sponsor
- Mahidol University · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital length of stay. Our focus centers on investigating the frailty index in the context of complications experienced by patients undergoing oncologic gynecology surgery. The principal objective of this research is to elucidate the extent to which residual neuromuscular blocking agents are linked to frailty.
Detailed description
Among patients undergoing oncologic gynecological procedures, such as those for vulvar cancer, endometrial cancer, and ovarian cancer, the incidence of frailty has been observed to range from 14% to 45%. Frailty directly influences the metabolism of anesthetic agents and intraoperative management. Furthermore, the prevalence of residual neuromuscular blocking agents following surgery can be as high as 26% to 53%. No prior research has investigated the correlation between residual muscle relaxants and frailty in gynecologic oncology patients. This study is designed to assess the prevalence of residual muscle relaxants in these patients with frailty. Additionally, data on the incidence of frailty and its impact on postoperative outcomes and prognosis in patients undergoing gynecologic oncology surgery will be collected and reported.
Conditions
- Frailty
- Neuromuscular Blockade
- General Anesthetic Drug Adverse Reaction
- Gynecologic Cancer
- Surgical Complication
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Train of four nerve stimulator | Patient receive nerve stimulation by TOF-scan equipment at recovery room after surgery. |
Timeline
- Start date
- 2024-01-02
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2024-01-22
- Last updated
- 2025-05-08
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT06216002. Inclusion in this directory is not an endorsement.