NCT06211465

Cardiovascular And Metabolic Risk After Arthroplasty

Cardiovascular And Metabolic Risk After Arthroplasty: the CAMERA Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 152 (actual)
• Sponsor: University of Tartu · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Osteoarthritis is a chronic joint disease that lacks curative therapy. Epidemiological studies show increase in the burden of disease. Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. However, the specific effects of total joint arthroplasty on cardiovascular risk and metabolic profile are largely unknown. The aim of this project is to elucidate how hip and knee total joint arthroplasty impacts cardiovascular risk and metabolomic profile in comparison with general population. We hypothesize that arthroplasty decreases pain, systemic inflammation levels and increases functional status that all lead to decreased metabolic and cardiovascular risk.

Conditions

• Osteoarthritis of the Knee
• Osteoarthritis of the Hip
• Cardiovascular Diseases
• Metabolic Syndrome

Interventions

Type	Name	Description
PROCEDURE	Total joint arthroplasty	Hip or knee total joint arthroplasty

Timeline

• Start date: 2014-03-01
• Primary completion: 2023-01-01
• Completion: 2023-04-01
• First posted: 2024-01-18
• Last updated: 2024-01-18

Locations

1 site across 1 country: Estonia