NCT06201351

Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI

Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction Magnetic Resonance Imaging (MRI)

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: West China Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The changes of target and organs at risk in patients with high-grade glioma during concurrent chemoradiotherapy were evaluated by MRI image between radiotherapy fractions.

Detailed description

To prospectively evaluate the changes of target organs and risk organs in patients with high-grade glioma during concurrent chemoradiotherapy.The related factors causing this change are discussed.The relationship between changes and patient survival was analyzed.A predictive model was established to provide individualized adaptive radiotherapy for patients.

Conditions

• High-grade Glioma

Interventions

Type	Name	Description
DEVICE	adaptive radiotherapy	MRI was performed and adaptive radiotherapy was administered at farction10 and fraction 20 during radiotherapy.

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-12-01
• Completion: 2026-09-30
• First posted: 2024-01-11
• Last updated: 2024-01-11

Locations

1 site across 1 country: China

Regulatory

• FDA-regulated device study