NCT06196515

Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication

Evaluation of the Antibacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication: A Randomized Clinical Trial

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 54 (estimated)
• Sponsor: British University In Egypt · Academic / Other
• Sex: All
• Age: 21 Years – 49 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to evaluate the anti-bacterial potential of Nano Calcium Hydroxide as an intracanal medication in primary endodontic treatment of permanent molars.

Detailed description

This study is conducted to evaluate the bacterial reduction capability of hydrogel loaded with Nano Calcium Hydroxide and paste form of nano and conventional calcium hydroxide as an intracanal medication. The hydrogel will be synthesized in a new rapid in situ form that can turn from liquid into gel when reaching body temperature. The efficacy of bacterial reduction will be compared with Nano Calcium Hydroxide and conventional Calcium Hydroxide in paste form. The evaluation is to be done by quantitative microbiological assessment of samples which are gained from the root canal before and after intracanal medication placement in roots of permanent molars, having PAI score ≥ 2.

Conditions

• Endodontic Disease
• Pulp Disease, Dental

Interventions

Type	Name	Description
DRUG	Calcium hydroxide	placement of intracanal medication for the three groups will be done after cleaning and shaping of the root canals and it will be left for one week.
DRUG	nano calcium hydroxide	placement of intracanal medication for the three groups will be done after cleaning and shaping of the root canals and it will be left for one week.

Timeline

• Start date: 2024-08-01
• Primary completion: 2025-09-01
• Completion: 2025-12-01
• First posted: 2024-01-09
• Last updated: 2024-08-19

Locations

1 site across 1 country: Egypt