NCT06192914

EPAP, Interviewstudy

Prospective Survey of the Repeated Occurrence of Anaphylactic Reactions in Patients with Food Allergies

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 322 (estimated)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to learn about repetitive anaphylactic reactions in food allergic patients and to compare the frequency of repetitive reactions between different elicitors in food allergic patients. The main question it aims to answer are: • Is there an elicitor specific difference in the occurrence of anaphylactic reactions once the elicitor has been identified and the patient received counselling about its avoidance? Participants will answer questionnaires via a link they will receive via e-mail at baseline and 3, 6, 12 and 24 months after inclusion in the study.

Detailed description

The aim of the study is to establish a cohort of patients who were included in the anaphylaxis registry with an anaphylactic reaction to legumes, tree nuts, seeds, grains or pseudocereals within the previous twelve months. Patients are requested to provide information about the occurrence of new allergic reactions at defined time-points over a period of two years (at baseline, 3, 6, 12, and 24 months). In addition, their eating behavior and the food allergy-specific quality of life will be captured. The investigators intend to track self-management in dealing with anaphylaxis, especially the use of emergency medication. It is examined whether patients react again and whether these are reactions to a known or previously unknown allergen to the patient. By recording the symptoms, it will be checked whether there are certain reaction patterns to specific foods or whether these are patient specific. In addition, the influence of the previous anaphylactic reaction and knowledge of the existing allergy on quality of life, dietary behavior and the ability to use emergency medication should be examined. This is intended to help improve the care for future patients in order to minimize the risk of repeat reactions.

Conditions

• Food Allergy
• Food Allergy Peanut
• Allergy
• Anaphylactic Shock

Timeline

• Start date: 2022-03-01
• Primary completion: 2029-02-28
• Completion: 2029-02-28
• First posted: 2024-01-05
• Last updated: 2025-02-13

Locations

1 site across 1 country: Germany