NCT06187454

Transcranial Direct Current Stimulation for Depression

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Taipei Veterans General Hospital, Taiwan · Other Government
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

Several studies have shown that tDCS is valuable and safe options to improve depressive symptoms in adult patients . However, regarding the tDCS to treat depression in elderly population, only few studies have been reported, and there is no consensus among them. To our knowledge, prefrontal cortex tDCS could be reasonably safe and efficient options for the treatment of several psychiatric illnesses in a population presenting resistance to and/or intolerance of pharmacotherapy . Moreover, the safety tolerability profile of tDCS is a strong argument in favour of exploring their use in the depressed population. Therefore, current study will investigate the efficacy and safety of prefrontal tDCS used as additive treatment in patients with LLD.

Conditions

• Depressive Disorder

Interventions

Type	Name	Description
DEVICE	Active Transcranial direct current stimulation	Transcranial direct current stimulation (tDCS) is a method for noninvasive brain stimulation, where a weak electrical current is delivered through two scalp electrodes by a portable battery-powered stimulator.
DEVICE	Sham Transcranial direct current stimulation	For sham tDCS, the electrode positions and stimulation parameters will be the same as that used for anodal stimulation except that the current will be delivered only for the initial 30 seconds.

Timeline

• Start date: 2020-09-08
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2024-01-02
• Last updated: 2024-01-02

Locations

1 site across 1 country: Taiwan