NCT06180603

Strategy for Prompt and Effective Thoracentesis in the Emergency Department

Strategy for Prompt and Effective Thoracentesis in the Emergency Department: A Multicenter Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 188 (estimated)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The SPEEDTAP-trial is a prospective, randomised, investigator-initiated, multicenter, clinical superior trial investigating two thoracentesis methods in four emergency departments (ED) in Central Denmark Region. Patients are randomised to either manual fluid removal in the ED or passively fluid drainage using gravity in the radiology department (standard of care). Primary outcome: time from clinical indication to complete drainage and 188 patients will be included. Key secondary outcomes include length of stay, ED admission to ED discharge and safety end-points.

Conditions

• Pleural Effusion
• Pleural Diseases
• Heart Failure

Interventions

Type	Name	Description
PROCEDURE	Gravity fluid drainage in the radiology department	Patients will be referred to the radiology department. Thoracentesis will be performed according to local guidelines.
PROCEDURE	Manual drainage in the emergency department	Thoracentesis will be performed according to current guidelines in the emergency department. Fluid will manually be drained using a syringe connected to a three-way stopcock. Thoracentesis will be stopped early if:

Timeline

• Start date: 2024-01-15
• Primary completion: 2025-11-30
• Completion: 2025-12-31
• First posted: 2023-12-22
• Last updated: 2024-12-05

Locations

6 sites across 1 country: Denmark