NCT06168461

Daily Aspirin Treatment After Preeclampsia

Aspirin for the Treatment of Vascular Dysfunction After Preeclampsia

• Status: Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Anna Stanhewicz, PhD · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent this disease progression. This study addresses this public health issue by examining whether starting low dose aspirin therapy after pregnancy is an effective treatment for lasting blood vessel damage in order to inform better clinical management of cardiovascular disease risk in women who have had preeclampsia.

Conditions

• Preeclampsia

Interventions

Type	Name	Description
DRUG	Aspirin	162mg aspirin capsule
DRUG	Placebo	placebo capsule

Timeline

• Start date: 2023-11-01
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2023-12-13
• Last updated: 2025-12-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study