NCT06146322

Barley Beta-glucan, Glycemic Control, and Appetite

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Washington State University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Novel barley varieties high in the soluble fiber β-glucan have the capacity to improve population health through improving glycemic control. Sweetened and unsweetened wholegrain barley foods were tested in a randomized, controlled, crossover human clinical trial to assess impact on postprandial appetite and food intake.

Conditions

• Diet, Healthy
• Blood Sugar; High
• Diabetes
• Appetite and General Nutritional Disorders
• Appetitive Behavior

Interventions

Type	Name	Description
OTHER	WR	Unsweetened preload condition: 240 mL white glutinous rice, 250 kcal, 0 g β-glucan
OTHER	LB	Unsweetened preload condition: 240 mL low β-glucan barley, 250 kcal, \~4 g β-glucan
OTHER	MB	Unsweetened preload condition: 240 mL medium β-glucan barley, 250 kcal, \~5 g β-glucan
OTHER	HB	Unsweetened preload condition: 240 mL high β-glucan barley, 250 kcal, \~6 g β-glucan
OTHER	WR+50g HFCS	Sweetened condition with high fructose corn syrup (HFCS): 240 mL white glutinous rice + 50g HFCS, 391 kcal, 0 g β-glucan
OTHER	LB + 50 g HFCS	Sweetened condition with high fructose corn syrup (HFCS): 240 mL low β-glucan barley + 50 g HFCS, 391 kcal, \~4 g β-glucan
OTHER	MB + 50 g HFCS	Sweetened condition with high fructose corn syrup (HFCS): 240 mL medium β-glucan barley + 50 g HFCS, 391 kcal, \~5 g β-glucan
OTHER	HB + 50 g HFCS	Sweetened condition with high fructose corn syrup (HFCS): 240 mL high β-glucan barley + 50 g HFCS, 391 kcal, \~6 g β-glucan

Timeline

• Start date: 2019-10-01
• Primary completion: 2020-10-31
• Completion: 2020-10-31
• First posted: 2023-11-24
• Last updated: 2023-11-24

Locations

1 site across 1 country: United States