Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06141668

Optimal Stimulation Parameters to Disrupt Epileptiform Activity

Optimal Stimulation Parameters for Spike-ripple Disruption in Patients Undergoing Invasive Monitoring

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Massachusetts General Hospital · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Open-loop electrical stimulation has been found to reduce spike activity and seizures, but determining the optimal parameters to achieve these effects requires a brute force trial-and-error approach that relies on subjective physician discretion. We will compare the performance of stimulation parameters identified in rodent models to the recommended parameters for neuromodulation used in clinical practice.

Conditions

Interventions

TypeNameDescription
OTHERNeurostimulationElectrical stimulation

Timeline

Start date
2023-06-13
Primary completion
2025-11-30
Completion
2026-11-30
First posted
2023-11-21
Last updated
2024-11-20

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT06141668. Inclusion in this directory is not an endorsement.