Trials / Unknown
UnknownNCT06131008
Diastology-Guided Management of Decompensated Heart Failure
DiastologY-Guided MaNAgement of DecoMpensated Heart Failure: A Pilot RandomIzed, Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- McMaster University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
More than 30% of people hospitalized with decompensated heart failure return to the hospital within 90 days. Emerging evidence suggests that hemodynamic monitoring with guided management may enhance prognosis and management. Hemodynamic monitoring with echocardiography using diastology and an evidence-informed therapeutic protocol have the potential to achieve this aim in a minimally invasive manner.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Diastology | We will follow American Society of Echocardiography criteria to determine the degree of diastolic dysfunction after performing each focused echocardiogram. |
| BEHAVIORAL | Diastology-Guided Diuresis | If the daily urine output or weight loss are less than study-specified targets, then the research team will recommend changes to the diuretic regimen based on the degree of diastolic dysfunction. |
| BEHAVIORAL | Usual Care | Clinicians will rely on usual care metrics and parameters to guide diuresis. |
Timeline
- Start date
- 2023-11-06
- Primary completion
- 2024-04-08
- Completion
- 2024-07-31
- First posted
- 2023-11-14
- Last updated
- 2023-11-14
Source: ClinicalTrials.gov record NCT06131008. Inclusion in this directory is not an endorsement.