NCT06129643

Efficacy of Lasers in Root Canal Treatment, Part II: Postoperative Pain

Efficacy of 2780 nm Er,Cr:YSGG and 940 nm Diode Lasers in Root Canal Treatment, Part II: Postoperative Pain

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Future University in Egypt · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in post operative pain between conventional irrigation and the two types of lasers used. Forty-five patients are equally divided into 3 separate groups : * Group A (Conventional): 2.5% NaOCL and 17% EDTA. * Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination * Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient is given pain scale chart Numeric Rating Scale (NRS) to record his/her pain level before any endodontic treatment. All data will be collected, tabulated, summarized, and statistically analyzed.

Detailed description

Postoperative pain is a common complication following conventional endodontic treatment. According to a systematic review, the frequency of endodontic postoperative pain is between 3% and 58% of patients.Postoperative pain is attributed to chemical, mechanical and microbiological factors. Residual microorganisms remaining due to the complexity of the root canal system and the limited penetration capability of conventional irrigants are directly responsible for Post operative pain The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in post operative pain between conventional irrigation and the two types of lasers used. Forty-five patients are equally divided into 3 separate groups : * Group A (Conventional): 2.5% NaOCL and 17% EDTA. * Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination * Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient will be given pain scale chart (NRS scale) to record his/her pain level before any endodontic treatment. After disinfection, local anesthetic, tooth isolation, access cavity preparation and final obturation. Patients are asked to mark on a numeric rating scale (NRS) to determine incidence of postoperative pain and rate its intensity at 6, 12, 24, 48, 72 hours, and 7 days after the procedure All data will be collected, tabulated, summarized, and statistically analyzed.

Conditions

• Pulp Necroses
• Apical Periodontitis
• Pulp Disease, Dental

Interventions

Type	Name	Description
DRUG	Conventional group	conventional disinfection using 2.5% sodium hypochlorite and 17% EDTA
DEVICE	Dual laser group	Er,Cr:YSGG intracanal laser irradiation to remove smear layer followed by diode laser for disinfection
COMBINATION_PRODUCT	Combined group	17% EDTA was used to remove smear layer followed by diode laser for disinfection

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-10-30
• Completion: 2023-02-01
• First posted: 2023-11-13
• Last updated: 2026-03-11

Locations

1 site across 1 country: Egypt