NCT06124170

Improved Pain Management in Knee Osteoarthritis-related Surgeries

Evaluating the Effectiveness of Continuously Improved Pain Management in Knee Osteoarthritis-related Surgeries

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 714 (actual)
• Sponsor: Peng Liu · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In recent years, pain management coordinated with enhanced recovery after surgery (ERAS) has been widely applied and rapidly developed in orthopedics, showing promising prospects. Since 2016, our hospital has used a series of continuously improved pain management schemes for patients with knee OA who underwent total knee arthroplasty (TKA), unicompartmental knee arthroplasty (UKA), and high tibial osteotomy (HTO). Here, we retrospectively analyze these patients' clinical data to compare the effects of different pain intervention measures during the perioperative period on postoperative pain, functional exercise, hospital stay, and prognosis of the three surgical methods in an attempt to provide a feasible solution for pain management of these patients.

Detailed description

We retrospectively analyzed the clinical data of patients with knee osteoarthritis (OA) who received surgical treatment to provide a feasible solution for perioperative pain management of these patients. The medical records of 714 patients with knee OA who had undergone total knee arthroplasty (n=551), unicompartmental knee arthroplasty (n=92) and high tibial osteotomy (n=71) were retrospectively analyzed and the cases were divided into Groups A, B, and C, according to the continuously optimized pain management. Clinical data including anesthesia grade, surgery time, functional exercise, hospital stay, pain, emotion, complications and prognosis were compared.

Conditions

• Knee Osteoarthritis
• Total Knee Arthroplasty
• Unicompartmental Knee Arthroplasty
• High Tibial Osteotomy
• Pain Management

Interventions

Type	Name	Description
PROCEDURE	Preoperative pain managment	propaganda and education on pain; Preemptive analgesia with celecoxib (200 mg bid) 2 days before surgery
PROCEDURE	Intraoperative pain managment	Squeeze to expel blood (tourniquet); Before skin suture, 20 mL 0.5% ropivacaine was given subcutaneously for local infiltration anesthesia;
PROCEDURE	Postoperative pain managment	The intravenous analgesia pump was placed until 48 h after surgery;On the second day after surgery, celecoxib (200 mg bid) was administered orally, and buprenorphine transdermal patch was applied externally until hospital discharge;FNB catheter was placed under the guidance of ultrasound and connected with an analgesic pump, the anesthesia lasted until 48 h after surgery ‡

Timeline

• Start date: 2016-03-01
• Primary completion: 2022-03-02
• Completion: 2023-03-02
• First posted: 2023-11-09
• Last updated: 2023-11-09

Locations

1 site across 1 country: China