NCT06113965

Neural Operant Conditioning

Neural Operant Conditioning to Improve Walking After Stroke

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: MetroHealth Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient. The main questions it aims to answer are: * Can participants self-regulate reflex excitability * Can participants self-regulate reflex, reduce spasticity and improve walking Participants will undergo surface stimulation to evoke spinal reflexes and will be asked to control these reflexes therefore reducing spasticity. Researchers will compare result to able bodied participants to see if \[insert effects\]

Detailed description

The study purpose is to investigate the possibility and later effect of spinal reflex self-regulation in post-stroke stiff-knee gait. The intervention will consist of direct current surface stimulation of the peripheral nerves using electrical stimulation. Stimulation will evoke a motor response that will be collected through surface EMG electrodes and processed to depict a measure of the response as feedback to the participant to complete the loop of operant conditioning. The participant will attempt to modulate their responses over multiple sessions to cause this depiction to either increase or decrease its value depending on an established target. .

Conditions

• Stroke
• Chronic Stroke
• Gait, Hemiplegic
• Gait, Spastic
• Walking, Difficulty

Interventions

Type	Name	Description
DEVICE	Peripheral Nerve Stimulation	Electrical stimulation of peripheral nerves to measure resulting gait kinematics and surface muscle activity

Timeline

• Start date: 2024-12-31
• Primary completion: 2027-05-31
• Completion: 2028-05-31
• First posted: 2023-11-02
• Last updated: 2025-03-10

Locations

1 site across 1 country: United States