NCT06109532

Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 530 (estimated)
• Sponsor: Hospital Nacional Profesor Alejandro Posadas · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.

Detailed description

Background Dengue infection is becoming more prevalent worldwide and is associated with systemic inflammation. Systemic Inflammation is associated with non-osmotic release of ADH. Methods: Participants conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.

Conditions

• Hyponatremia
• Dengue
• Inflammation

Interventions

Type	Name	Description
OTHER	hyponatremia	hyponatremia at admission in dengue infected patients

Timeline

• Start date: 2016-01-01
• Primary completion: 2023-10-30
• Completion: 2023-10-31
• First posted: 2023-10-31
• Last updated: 2023-11-02

Locations

2 sites across 1 country: Argentina