NCT06096376

Predictors of HFNC Failure in Patients With AHRF Using Diaphragm Ultrasound

Predictors of High-Flow Nasal Cannula Failure (HFNC) in Patients With Acute Hypoxemic Respiratory Failure (AHRF) Using Diaphragm Ultrasound Parameters

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Queen Mary Hospital, Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Ultrasound of the diaphragm is an easily reproducible bedside tool that provides a non-invasive measurement of inspiratory muscle function and respiratory efficiency. The diaphragmatic thickness correlates with the strength and muscle shortening and is reflective of its contribution to the respiratory workload. Diaphragm thickening fraction (DTF) has been shown to be predictive of extubation failure in ventilated patients. However, whether measurements of DTF are predictive of high flow nasal cannula (HFNC) outcomes in patients with acute hypoxemic respiratory failure (AHRF) remains unknown. The objective of this study is to identify predictors of HFNC failure by diaphragm ultrasound and to compare its performance with the well-established ROX index.

Conditions

• Acute Hypoxemic Respiratory Failure

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Diaphragm Ultrasound	Diaphragm ultrasound to assess respiratory muscle function and respiratory efficiency

Timeline

• Start date: 2023-04-28
• Primary completion: 2024-06-26
• Completion: 2024-09-01
• First posted: 2023-10-23
• Last updated: 2024-10-17

Locations

1 site across 1 country: Hong Kong