NCT06087562

iPACK Block for Total Knee Arthroplasty

Interspace Between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) Block for Postoperative Rehabilitation in Total Knee Arthroplasty: a Randomized Control Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 350 (estimated)
• Sponsor: Poznan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee arthroplasty.

Detailed description

The Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block, has been recently described and shows promise in providing analgesia to the knee joint. The effect of this block on postoperative rehabilitation is uncertain. This study aims to compare a preoperative iPACK block to a placebo block prior to total knee arthroplasty under spinal anesthesia. The primary outcome measure is verticalization, walking distance, ability to go out of bed, active lifting of the limb, range of motion in the hip joint, bending range of motion, and abduction range of motion. The secondary measure is postoperative pain assessment during rehabilitation.

Conditions

• Knee Osteoarthritis
• Knee Pain Chronic
• Knee Disease

Interventions

Type	Name	Description
DRUG	Ropivacaine 0.5% Injectable Solution 20mL	Ultrasound-guided iPACK block with 20mL of 0,5% ropivacaine
DRUG	0,9% normal saline 20mL	Ultrasound-guided placebo block with 20mL of 0,9% normal saline

Timeline

• Start date: 2020-06-16
• Primary completion: 2024-09-30
• Completion: 2024-12-30
• First posted: 2023-10-18
• Last updated: 2023-10-18

Locations

1 site across 1 country: Poland