NCT06076187

Protein Digestion After Bariatric Surgery in Older Adults

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 72 (estimated)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to investigate protein digestibility after bariatric surgery. Does protein digestibility decrease after Roux-en-Y-Gastric Bypass? Does protein digestibility decrease after Sleeve Gastrectomy surgery? Does protein digestibility effect the ability to meet protein requirements?

Detailed description

Purpose of clinical trial is to investigate the digestion of dietary protein in older patients who have undergone Roux-and-Y Bypass (RYGB) or sleeve gastrectomy (SG) surgery. The primary objective is to compare dietary protein digestion during a test meal who have previously undergone a RYGB surgery, SG surgery, or control patients, using a dual stable-isotope method. The secondary objectives are to investigate the relationship between protein intake corrected for protein digestion and skeletal muscle mass, and to investigate the relationship between the rate of free amino acid appearance and protein digestion.

Conditions

• Overweight and Obesity
• Bariatric Surgery Candidate
• Aging
• Protein Malabsorption

Interventions

Type	Name	Description
OTHER	Dual isotope protein digestibility method	Dual isotope method

Timeline

• Start date: 2023-05-15
• Primary completion: 2026-11-25
• Completion: 2026-11-25
• First posted: 2023-10-10
• Last updated: 2025-02-28

Locations

2 sites across 1 country: Belgium