Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06075485

Management of Drug-resistant Epilepsy in Infants and Children: a Real-life Study of the Use of the Ketogenic Diet in France and the KetoCal® Range in Its Maintenance

Status
Recruiting
Phase
Study type
Observational
Enrollment
133 (estimated)
Sponsor
Nutricia Nutrition Clinique · Industry
Sex
All
Age
5 Months – 18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, prospective, observational, longitudinal study designed to describe the therapeutic value of the KetoCal® range in the maintenance of a ketogenic diet during the management of infants (from 5 months) and children up to 17 years of age (i.e. 18 years minus 1 day) with drug-resistant epilepsy. This study is being conducted according to standard medical practice. No change in diagnostic or therapeutic management habits is imposed by this study. Quality of life questionnaires are the only additional procedures for this research.

Detailed description

NUTRICIA has developed the KetoCal® range (4:1 and 3:1), a food for special medical purposes (DADFMS), to help healthcare professionals and patients establish and maintain a CR. KetoCal® 4:1 features a 4:1 ratio of fat to (carbohydrate + protein), while containing vitamins, minerals, trace elements and fiber. Similarly, KetoCal® 3:1 has a 3:1 ratio of lipids / (carbohydrates + proteins), while containing vitamins, minerals, trace elements and fiber. The KetoCal® range can be consumed orally, as a drink after dilution in hot water, incorporated as an ingredient in a recipe or administered by enteral feeding tube. The KEOPS study is designed to gather real-life data on the therapeutic value of using the KetoCal® range in the management of drug-resistant epilepsy in infants (from 5 months) and children up to 18 years of age. Patients will be managed according to standard care practices. Initiation of ketogenic dieting will be at the investigator's discretion during the child's hospitalization.

Conditions

Interventions

TypeNameDescription
OTHERKetocalketogene diet

Timeline

Start date
2024-01-15
Primary completion
2026-06-01
Completion
2026-06-01
First posted
2023-10-10
Last updated
2024-01-24

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT06075485. Inclusion in this directory is not an endorsement.