NCT06062511

Poplar-type Propolis Dry Extract ESIT12 : Nutrikinetic and Bioavailability Studies

Evaluation of Nutrikinetic and Bioavailability of Phenolic Compounds From ESIT12, a Poplar-type Propolis Dry Extract

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Fytexia · Industry
• Sex: All
• Age: 25 Years – 69 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate phenolic compounds from ESIT12, a poplar-type propolis ingredient, bioavailability and nutrikinetics by measuring urinary excretion and metabolic profile over 48h by means of high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS). The study follows a cross-over, double-blind, randomized and placebo control design on 10 healthy subjects.

Conditions

• Nutrition, Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	ESIT12 D	ESIT12 is a poplar-type propolis powder extract containing phenolic compounds from flavonoids and phenolic acids family. ESIT12 D contains 400 mg of ESIT12
DIETARY_SUPPLEMENT	ESIT12 4D	ESIT12 is a poplar-type propolis powder extract containing phenolic compounds from flavonoids and phenolic acids family. ESIT12 4D contains 1600 mg of ESIT12
DIETARY_SUPPLEMENT	Placebo	Placebo is composed of the carriers of ESIT12 : arabic gum, sucrose and silicon dioxide mix

Timeline

• Start date: 2023-07-22
• Primary completion: 2023-10-10
• Completion: 2023-10-10
• First posted: 2023-10-02
• Last updated: 2023-12-08

Locations

1 site across 1 country: Spain