Trials / Unknown
UnknownNCT06054126
COronary CoLLateralization in Type 2 diabEtic Patients With Chronic Total Occlusion
The Development of Coronary Collateralization in Type 2 Diabetic Patients With Chronic Total Occlusion
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 2,000 (estimated)
- Sponsor
- Ruijin Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
A severe coronary artery obstruction is a prerequisite for spontaneous collateral recruitment. The formation of coronary collateral circulation(CCC) is significantly impaired in type 2 diabetic patients with chronic total occlusion (CTO) compared with non-diabetic patients with CTO. This retrospective cohort enrolls consecutive T2DM patients who had at least one lesion with coronary angiographic total occlusion.
Detailed description
COronary CoLLateralization in Type 2 diabEtic Patients With Chronic Total Occlusion (COLLECT) study is a single center, retrospective cohort study to investigate potential factors associated with the development of coronary collateral circulation in diabetic patients. Investigators will consecutively enroll T2DM patients who had at least one lesion with coronary angiographic total occlusion. The development of coronary collateral circulation will be graded according to the Rentrop method and patients will be divided into poor CCC (grade 0 or 1) or good (grade 2 or 3) CCC groups according to their Rentrop grades. Baseline clinical and laboratory characteristics at hospital admission will be recorded to analyze potential factors associated with the development of coronary collateral circulation in T2DM patients with CTO. Later, their cardiac function will be evaluated by echocardiography at one year follow-up.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Echocardiography | Cardiac function was evaluated by echocardiography at one year follow-up. |
Timeline
- Start date
- 2010-01-01
- Primary completion
- 2025-12-31
- Completion
- 2026-03-01
- First posted
- 2023-09-26
- Last updated
- 2023-10-23
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06054126. Inclusion in this directory is not an endorsement.