NCT06045715

Follow-up Strategy for Esophageal Cancer Patients

An Optimized Post-surgery Follow-up Strategy for Patients With Esophageal Cancer

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 3,000 (actual)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The recurrence risk of patients with esophageal cancer was stratified by integrating different stages and pathological factors. The risk of recurrence was dynamically estimated for each group of patients, and the optimal follow-up strategy was developed based on the recurrence risk.

Detailed description

Patients with histologically proven, esophageal cancer (EC) patients diagnosed between 2008 and 2018 were recruited. Recursive partition analysis was applied to develop recurrence risk stratification for patients. The follow-up strategies of each stratification were developed based on monthly recurrence probability and validated by bootstrap validation and an external dataset. Markov decision-analytic models were constructed to evaluate the cost-effectiveness of the follow-up strategies.

Conditions

• Esophagus Cancer

Interventions

Type	Name	Description
OTHER	follow-up with different time intervals	After radical surgery, patients are followed up with different time intervals

Timeline

• Start date: 2022-08-20
• Primary completion: 2023-06-30
• Completion: 2023-12-01
• First posted: 2023-09-21
• Last updated: 2023-09-21

Locations

1 site across 1 country: China