NCT06010810

The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Indonesia University · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare 3% Topical Tranexamic Acid with 4% Topical Hydroquinone as Therapy of Melasma in Patients with Skin Type III-V. The main question\[s\] it aims to answer are: 1. Is there a greater decrease in mMASI score after application of 3% topical tranexamic acid compared to 4% hydroquinone in melasma patients with skin type III - V? 2. Is there a greater decrease in mexameter score after application of 3% topical tranexamic acid compared to 4% hydroquinone in melasma patients with skin type III - V? 3. Are there any side effects of topical therapy of 3% tranexamic acid cream on melasma patients with skin types III - V? Participants with melasma diagnostic will apply the tranexamic acid cream and hydroquinone cream on both sides of the face differently. Researchers will compare by measuring the mexameter score and mMasi score to see if there any decrease in both sides of the face.

Conditions

• Melasma

Interventions

Type	Name	Description
DRUG	3 % Topical Tranexamic Acid	Patient will be given 3% Topical Tranexamic Acid, on half of the face, twice a day for 2 months
DRUG	4% Topical Hidroquinone	Patient will be given 4% Topical Hidroquinone, on half of the face, twice a day for 2 months

Timeline

• Start date: 2023-06-01
• Primary completion: 2023-09-01
• Completion: 2023-09-30
• First posted: 2023-08-25
• Last updated: 2023-09-21

Locations

1 site across 1 country: Indonesia