NCT05983562

Examining the Feasibility of Prolonged Ketone Concentrate Supplement Drink Consumption in Adults With Type 2 Diabetes

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 30 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

Brief Summary: Ketones are a source of energy and signaling molecule that are produced by the body when not consuming any food or consistently eating a low-carbohydrate "keto" diet. Blood ketones can be used as a source of energy by the body, but they may also act as signals that impact how different cells in the body function. Recently, ketone supplements have been developed that can be consumed as a drink. These supplements can raise blood ketones without having to fast or eat a "keto" diet. Previous studies have shown that these supplement drinks can lower blood sugar without having to make any other dietary changes. Drinking these ketone supplements may therefore be an effective strategy to improve blood sugar control and influence how cells function. To find out if it is feasible for people with type 2 diabetes to drink these ketones supplements regularly over 90 days, we will compare between two groups in this study: one group that will be asked to drink ketone supplements, and one group that will be asked to drink a placebo supplement.

Conditions

• Diabetes Mellitus, Type 2
• Hyperglycemia
• Ketosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dietary Supplement: D-β-hydroxybutyric acid with R-1,3-butanediol	Pre-intervention (baseline) and post-intervention measurements will be obtained before and after the 90-day period respectively.
OTHER	Inert placebo	Pre-intervention (baseline) and post-intervention measurements will be obtained before and after the 90-day period respectively

Timeline

• Start date: 2023-06-26
• Primary completion: 2024-03-01
• Completion: 2024-03-01
• First posted: 2023-08-09
• Last updated: 2024-02-15

Locations

1 site across 1 country: Canada