NCT05981755

Breathing Rescue for SUDEP Prevention

Breathing Rescue for SUDEP Prevention (BreatheS)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to precisely delineate human brain networks that modulate respiration and identify specific brain areas and stimulation techniques that can be used to prevent seizure-induced breathing failure.

Conditions

• Focal Epilepsy

Interventions

Type	Name	Description
OTHER	Breathing tasks	Breathing tasks include normal breathing through nose or mouth, breathing while resting wakefully, increase and decrease in breathing rate, and breath counting.
DEVICE	Brain mapping with stimulation	Electrical stimulation will be used to find specific areas of the brain involved in breathing function. Stimulation will be applied using a Nihon Kohden MEE-1000A neural function measuring system with the MS-120BK extension unit for brain stimulation.

Timeline

• Start date: 2023-07-31
• Primary completion: 2028-06-30
• Completion: 2028-06-30
• First posted: 2023-08-08
• Last updated: 2025-06-18

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study