Trials / Unknown
UnknownNCT05979662
Endoscopic Frontal Sinus Surgery Draf III in Moderate to Severe Eosinophilic Chronic Rhinosinusitis With Polyps
Clinical Evaluation of Primary Endoscopic Frontal Sinus Surgery Grade 6 (Draf III) in Patients With Moderate to Severe Eosinophilic Chronic Rhinosinusitis With Polyps
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Ibrahim Talal Elshamy · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to evaluate the effect of the primary endoscopic frontal sinus surgery on the clinical outcome in patients having moderate to severe eosinophilic chronic rhinosinusitis with polyps with primary outcome measures in form of recurrence of polyp using endoscopic polyp score and Secondary outcome measures include Lund MacKay score, SNOT-22 and need for corticosteroid to control polyp postoperatively.
Detailed description
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder, affecting about 4% of the population worldwide and strongly impacts the quality of life of affected patient. Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of recalcitrant Chronic rhinosinusitis . Patients with ECRS and generally having a tissue eosinophil \>10 cells per high power field (HPF), have worse disease severity and poorer treatment outcomes compared to non-Eosinophilic chronic rhinosinusitis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Endoscopic frontal sinus surgery grade 6(Draf III). | Patients will receive endoscopic frontal sinus surgery grade 6(Draf III). |
| PROCEDURE | Endoscopic frontal sinus surgery grade 1-3(Draf I or IIa) | Patients will receive endoscopic frontal sinus surgery grade 1-3(Draf I or IIa). |
Timeline
- Start date
- 2021-01-01
- Primary completion
- 2023-09-30
- Completion
- 2023-09-30
- First posted
- 2023-08-07
- Last updated
- 2023-08-07
Locations
2 sites across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05979662. Inclusion in this directory is not an endorsement.