NCT05969756

Early Treatments for Preventing Occlusal Caries Lesions

Clinical Effectiveness of Early Treatments for Preventing Occlusal Caries Lesions in Erupting Permanent Molars

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 114 (estimated)
• Sponsor: Hue University of Medicine and Pharmacy · Academic / Other
• Sex: All
• Age: 5 Years – 14 Years
• Healthy volunteers: Accepted

Summary

Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially erupted permanent molars. This study aims to evaluate the progression of caries, the degree of retention, survival rate, and quality of the remnant after applying conventional total-etch resinous sealant and self-etch sealant in erupting molars.

Conditions

• Caries; Initial
• Occlusal Caries
• Caries,Dental

Interventions

Type	Name	Description
DRUG	Fluoride varnish	Thirty-eight permanent molars will receive 5% sodium fluoride varnish application every three months
DRUG	Conventional etch and rinse sealant	Thirty-eight permanent molars will receive conventional etch and rinse sealant
DRUG	Self-etch sealant	Thirty-eight permanent molars will receive self-etch sealant

Timeline

• Start date: 2023-07-31
• Primary completion: 2024-10-10
• Completion: 2024-10-15
• First posted: 2023-08-01
• Last updated: 2024-09-20

Locations

2 sites across 1 country: Vietnam