NCT05968586

Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants

Effect of Body Position on Oxygenation, Ventilation, and Diaphragmatic Workload in Premature Infants on Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: All
• Age: 1 Minute – 3 Months
• Healthy volunteers: Not accepted

Summary

This research study is being done to investigate the effect of changing an infant's body position on how hard the baby works to breathe, the baby's oxygen level, the baby's carbon dioxide level, the baby's lung volume, the baby's lung compliance (ability of the lung to expand and fill with air), and how frequently the baby develops clinically significant events such as apnea (baby stops breathing on his own), bradycardia (low heart rate), and desaturation (low oxygen) events.

Conditions

• Neonatal Oxygen Desaturation
• Premature
• Ventilator Lung; Newborn
• Apnea of Prematurity

Interventions

Type	Name	Description
OTHER	Body positioning	Body positioning of infants prone vs supine.

Timeline

• Start date: 2023-09-11
• Primary completion: 2024-12-28
• Completion: 2024-12-31
• First posted: 2023-08-01
• Last updated: 2025-01-29

Locations

1 site across 1 country: United States