Trials / Completed
CompletedNCT05964465
Mechanisms of Smell Improvement With Dupilumab.
Mechanisms of Smell Improvement With Dupilumab
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Medical University of South Carolina · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study seeks to explore the mechanism through which dupilumab improves olfactory cleft inflammation in patients with chronic sinusitis with nasal polyps (CRSwNP). The investigators expect this study to provide convincing evidence that dupilumab improves clinical olfaction via direct reduction in olfactory cleft inflammation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dupilumab | Monoclonal antibody blocking interleukin 4 and interleukin 13 |
Timeline
- Start date
- 2023-08-10
- Primary completion
- 2025-01-30
- Completion
- 2025-01-30
- First posted
- 2023-07-28
- Last updated
- 2026-02-17
Locations
2 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05964465. Inclusion in this directory is not an endorsement.