NCT05957211

Improving Drop Instillation Comfort of a Cyclosporine A Solution

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of Waterloo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients who suffer from dry eye disease are often prescribed eye drops containing cyclosporine A that help with reducing inflammation. The newest eye drop containing cyclosporine A is called Cequa (Sun Pharma, Canada). Unfortunately, nearly a quarter of (24.2%) of patients using Cequa have reported some form of discomfort (burning and stinging) when instilling the drops. This potentially discourages patients from continuing the eye drop, which prevents their dry eye disease from being managed effectively. This study is trying to determine if refrigerating the eye drops would allow the drops to feel more comfortable when they are instilled in the eye.

Conditions

• Dry Eye Disease

Interventions

Type	Name	Description
DRUG	0.09% cyclosporine A ophthalmic solution	Cequa is an ophthalmic solution used to treat moderate to severe dry eye disease. The typical dosage is one drop in each eye, twice a day. The drug is packaged in sterile, single use bottles.

Timeline

• Start date: 2023-05-19
• Primary completion: 2024-02-20
• Completion: 2024-02-20
• First posted: 2023-07-24
• Last updated: 2024-08-09

Locations

1 site across 1 country: Canada