NCT05941754

A Clinical Study of Omega-3 on Depression and Cognition

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Nanfang Hospital, Southern Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Depression is a serious mental illness, with persistent depression and loss of interest as the main clinical manifestations, and causes varying degrees of cognitive impairment, further leading to impaired social function, and even lead to suicidal behavior. Previous studies on the antidepressant effects of Omega-3 mainly focused on chronic effects, and there was a lack of corresponding rapid response clinical studies. Because of the nature of Omega-3 health products, no clinical adverse effects have been reported. We have previously shown that Omega-3 can produce antidepressant and cognitive improvement effects. This study will carry out different doses (low dose and high dose) and single active ingredient (EPA alone) to observe the antidepressant and cognitive improvement effects of Omega-3 in clinical patients with major depression. The antidepressant effect and cognitive improvement effect of Omega-3 will be further verified to provide evidence for future clinical application.

Conditions

• Depression

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	omega-3	supplement in the market
DIETARY_SUPPLEMENT	placebo	corn oil

Timeline

• Start date: 2022-12-15
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2023-07-12
• Last updated: 2023-07-12

Locations

1 site across 1 country: China