Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05939453

Impact of Bright Light Therapy on Prader-Willi Syndrome

A Randomized, Double-Blind, Controlled Trial of Bright Light Therapy on All-Cause Excessive Daytime Sleepiness in Prader-Willi Syndrome

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Maimonides Medical Center · Academic / Other
Sex
All
Age
6 Years – 88 Years
Healthy volunteers
Not accepted

Summary

This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome

Detailed description

This is a prospective, placebo controlled, open label clinical trial that examines light therapy as a treatment for excessive daytime sleepiness in patients with Prader-Willi syndrome. Subjects are assessed for changes in mood, behavior, body weight, and hyperphagia during visits. All visits are conducted remotely. There are a total of 8 visits occurring over the course of 8 weeks. After the first visit, all study visits occur on a weekly basis. Individuals between the ages of 6-18 years old with diagnosis of PWS confirmed by genetic testing will be screened for enrolment by the study team.

Conditions

Interventions

TypeNameDescription
OTHERSham LightSham treatment will be provided from a light box at a distance of at least 70cm but no greater than 90cm.
OTHERBright Light TherapyBright Light Therapy will be provided using light box with an artificial full spectrum lamp at a distance of at least 70cm but no greater than 90cm.

Timeline

Start date
2023-10-01
Primary completion
2026-01-01
Completion
2026-06-01
First posted
2023-07-11
Last updated
2025-02-26

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05939453. Inclusion in this directory is not an endorsement.