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Trials / Active Not Recruiting

Active Not RecruitingNCT05910528

Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease

A Phase 2, Multicenter, Double-blind, Two-arm Study of Subcutaneous RO7790121 for the Treatment of Subjects With Moderate to Severe Active Crohn's Disease

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
21 (actual)
Sponsor
Hoffmann-La Roche · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This Phase 2, randomized, double-blind, multicenter, induction and maintenance study is designed to evaluate the safety and efficacy of Afimkibart (RO7790121, RVT-3101) in adult participants with moderate to severe active Crohn's disease.

Conditions

Interventions

TypeNameDescription
DRUGAfimkibartAfimkibart will be administered during the Induction, Maintenance and OLE period.

Timeline

Start date
2023-07-24
Primary completion
2030-12-31
Completion
2030-12-31
First posted
2023-06-18
Last updated
2026-03-24

Locations

11 sites across 4 countries: United States, Belgium, France, Poland

Regulatory

Source: ClinicalTrials.gov record NCT05910528. Inclusion in this directory is not an endorsement.