Clinical Trials Directory

Trials / Terminated

TerminatedNCT05906251

A Gene Transfer Study to Evaluate the Safety, Tolerability and Efficacy of SRP-6004 in Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2B/R2 (LGMD2B/R2, Dysferlin [DYSF] Related)

An Open-Label, Systemic Gene Transfer Study to Evaluate the Safety, Tolerability, and Efficacy of SRP 6004 Administered by Systemic Infusion in Ambulatory Subjects With Limb Girdle Muscular Dystrophy Type 2B/R2 (LGMD2B/R2, Dysferlin Related)

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
2 (actual)
Sponsor
Sarepta Therapeutics, Inc. · Industry
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to evaluate the safety of SRP-6004 administered by intravenous (IV) infusion in ambulatory participants with LGMD2B/R2 (DYSF related).

Conditions

Interventions

TypeNameDescription
GENETICSRP-6004Single IV infusion of SRP-6004

Timeline

Start date
2023-05-22
Primary completion
2025-06-13
Completion
2025-06-13
First posted
2023-06-15
Last updated
2025-09-04

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05906251. Inclusion in this directory is not an endorsement.

A Gene Transfer Study to Evaluate the Safety, Tolerability and Efficacy of SRP-6004 in Ambulatory Participants With Limb (NCT05906251) · Clinical Trials Directory