NCT05897567

Effect of Ketogenic Diet on Muscle Hypertrophy

Effects of Ketogenic Diet on Muscle Hypertrophic Response to Resistance Exercise

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Padova · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate the effects of 4 weeks of carbohydrate deprivation (through a ketogenic diet) on hypertrophy signalling after a single bout of exercise in healthy trained male subjects, and the impact on body composition, muscle strength, and blood parameters.

Conditions

• Healthy Nutrition

Interventions

Type	Name	Description
OTHER	resistance training	All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.
OTHER	ketogenic diet	Subjects allocated to the ketogenic diet arm (KD group) consume less than 50 g of carbohydrates per day.
OTHER	western diet	Subjects allocated to the western diet arm (WD group) consume a standard diet based on 55% of their daily calories from carbohydrates.

Timeline

• Start date: 2023-06-20
• Primary completion: 2025-03-31
• Completion: 2025-12-31
• First posted: 2023-06-09
• Last updated: 2024-05-10

Locations

1 site across 1 country: Italy