NCT05886699

Comparison of PRP & DFDBA vs. DFDBA in Intrabony Periodontal Defects

Comparison of Efficacy of Autologous Platelet - Rich Plasma Combined With Demineralized Freeze - Dried Bone Allograft Versus Demineralized Freeze - Dried Bone Allograft: A Randomized Clinical Trial in Central India

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Government Dental College and Hospital, India · Other Government
• Sex: All
• Age: 28 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this clinical trial is to compare the results in subjects with periodontitis using subjects own blood - Platelet-rich plasma (PRP) combined with bone graft material, namely, Demineralized Freeze - Dried Bone Allograft (DFDBA) or DFDBA alone in the treatment of bone defects around the teeth.

Detailed description

After being informed about the study and potential risks, 13 patients giving written informed consent and who meet the eligibility requirements were randomly allocated in a single blind manner (participants) to test group (PRP combined with DFDBA) or control group (DFDBA). 33 sites (18 test, 15 control unpaired defects) were treated - 1) to investigate the possible additional effects of PRP when combined with DFDBA, and 2) to compare the clinical and radiographic outcomes obtained in test and control groups,12 months post - operatively.

Conditions

• Chronic Periodontitis

Interventions

Type	Name	Description
OTHER	PRP combined with DFDBA	Periodontal intrabony defects were treated with open flap debridement followed by placement of PRP combined with DFDBA
OTHER	DFDBA	Periodontal intrabony defects were treated with open flap debridement followed by placement of PRP combined with DFDBA

Timeline

• Start date: 2012-01-01
• Primary completion: 2012-12-01
• Completion: 2013-12-01
• First posted: 2023-06-02
• Last updated: 2023-06-02

Locations

1 site across 1 country: India