NCT05884099

Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection

Intercostal Cryoanalgesia for Prevention of Chronic Postoperative Pain Following Video-assisted Thoracoscopic Lung Cancer Resection

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the prevention of chronic thoracic pain after VATS lung resection surgery.

Detailed description

VATS lung resection is associated with a high incidence of persistent thoracic pain. To our knowledge, there is no study on the effect of cryoanalgesia on the incidence and severity of chronic thoracic pain 3 months after VATS lung resection. Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. In a recent study by Ilfeld \& al, intercostal cryoanalgesia (combined with a single-injection paravertebral block) was able to drastically lower the incidence of chronic pain after total mastectomy compared to the use of the paravertebral block alone (3% vs 17%). The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia for the prevention of chronic thoracic pain after VATS lung resection surgery.

Conditions

• Cryotherapy Effect
• Chronic Pain
• Lung Cancer
• Surgery

Interventions

Type	Name	Description
PROCEDURE	Cryoanalgesia AND single-injection paravertebral block	CO2 Cryoanalgesia AND paravertebral block with Bupivacaine 0.5%
PROCEDURE	Single-injection paravertebral block	Paravertebral block with Bupivacaine 0.5%

Timeline

• Start date: 2023-11-09
• Primary completion: 2025-01-21
• Completion: 2025-04-21
• First posted: 2023-06-01
• Last updated: 2025-07-04

Locations

1 site across 1 country: Canada