NCT05872126

Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 5 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases. Management of symptomatic malignant pleural effusion remains to be a point of debate. Data available from literature shows conflicting results lacking high quality evidence which necsscitates further research work. Options differs to include chemical pleurodesis using medical or surgical talc poudrage or slurry. Surgical intervention with abrasion pleurodesis or pleurectomy using VATS approach has been used in many studies. Using indwelling pleural catheters (IPCs) has also proved comparable efficacy at many clinical trials. In this study we want to help answering this question so that we can add to the current knowledge aiming to offer the best care for those patients

Conditions

• Malignant Pleural Effusion
• Thoracic Cancer

Interventions

Type	Name	Description
PROCEDURE	VATS-Surgical pleurodesis	VATS drainage and surgical abrasion.
PROCEDURE	Tube Drainage	Tube drainage for malignant pleural effusion

Timeline

• Start date: 2023-04-01
• Primary completion: 2025-03-31
• Completion: 2025-04-30
• First posted: 2023-05-24
• Last updated: 2023-05-24

Locations

1 site across 1 country: Egypt