Trials / Active Not Recruiting
Active Not RecruitingNCT05863052
Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population
Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population Treated With Immune Checkpoint Inhibitors for Various Cancers
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 72 (estimated)
- Sponsor
- University of Oklahoma · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to describe the outcomes in American Indian patients receiving immunotherapy in a multi-institution retrospective study at several other high-volume centers that care for this patient population and to identify any healthcare disparities that can lead to future interventional studies.
Detailed description
Immune checkpoint inhibitors have been shown to increase survival in metastatic solid tumor patients when compared to the previously standard of care chemotherapy. Epidemiologic studies of American Indian cancer patients demonstrated having significantly worse survival when compared with Caucasians when controlled for age, sex, alcohol abuse, smoking, insurance, and disease stage. There are no current studies specifically examining the American Indian population receiving treatment with immune checkpoint inhibitors. The aim is to describe the outcomes in American Indian patients receiving immunotherapy in a multi-institution retrospective study at several other high-volume centers that care for this patient population and to identify any healthcare disparities that can lead to future interventional studies.
Conditions
- Immune Checkpoint Inhibitors
- Metastatic Solid Tumor
- Nonsmall Cell Lung Cancer
- Melanoma
- Renal Cell Carcinoma
- Gastrointestinal Cancer
- Squamous Cell Carcinoma
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Immunotherapy | immunotherapy |
Timeline
- Start date
- 2022-01-31
- Primary completion
- 2026-12-01
- Completion
- 2027-12-01
- First posted
- 2023-05-17
- Last updated
- 2026-02-10
Locations
6 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05863052. Inclusion in this directory is not an endorsement.