NCT05859451

Effect of Tobacco Heating System (THS) on Closed Lower Limb Fracture Healing

Evaluation of Tobacco Heating System (THS) Compared to Conventional Cigarette Smoking During the Closed Lower Limb (Tibia and Femur) Fracture Healing in Orthopedic Smokers' Patients

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to investigate the role of switching from cigarette smoking (CS) to tobacco heat system (THS) on the clinical outcome of closed lower limb (tibia and femur) fractures from smokers' orthopedic patients. Validated and standardized assays, medical state and self-reported outcomes will be evaluated in orthopedic patients' smokers or switch from CS to using THS throughout six months compare to ex-smokers (control).

Conditions

• Smoking
• Tibia Fracture

Interventions

Type	Name	Description
DEVICE	Tobacco Heating System (THS)	Participant who are not willing to quit cigarette smoking during the study duration will switch from cigarettes to using THS
OTHER	Smoking abstinence	Participant who are willing to quit cigarette smoking and will not use any electronic nicotine delivery system during the study duration

Timeline

• Start date: 2023-06-02
• Primary completion: 2025-10-15
• Completion: 2026-04-17
• First posted: 2023-05-16
• Last updated: 2024-12-11

Locations

1 site across 1 country: Germany