NCT05852327

Risk Stratifying COPD Exacerbations

Risk Stratifying COPD Exacerbations: a Prospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Pamela Youde Nethersole Eastern Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: —

Summary

To identify clinical characteristics on presentation which predict differential outcomes in patients with exacerbation of COPD.

Detailed description

Exacerbations of COPD (ECOPD) are heterogenous but are often considered as a single clinical entity. Clinical characteristics on presentation may predict outcome of patients with ECOPD. DECAF score was previously proposed to predict in-hospital mortality but has not been validated in Asian subjects. ROME classification was recently proposed to better risk stratify ECOPD according to symptoms, physiological parameters and laboratory findings on admission, but no prospective validation study is available so far. This study aims to identify clinical characteristics on presentation to predict outcome of patients with ECOPD.

Conditions

• COPD Exacerbation

Interventions

Type	Name	Description
OTHER	Observation only	Observation only

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-02-01
• Completion: 2025-02-01
• First posted: 2023-05-10
• Last updated: 2023-12-27

Locations

2 sites across 1 country: Hong Kong