NCT05836532

Long Term Results of Surgical and Percutaneous Double Orefices Mitral Repair in Patient With p2 Prolapse Causing Degenerative Mitral Regurgitation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: Michele De Bonis · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Mitral regurgitation is a pathology affecting the left atrioventricular valve that causes a volumetric and pressure overload in the left chambers due to the loss of unidirectionality normally guaranteed by the cardiac valve system. The gold standard for severe mitral regurgitation is currently mitral valve plastic surgery. Edge to edge, on the other hand, allows shorter CEC and aortic clamping times and does not require significant surgical experience in the field of mitral valve repair, therefore edge to edge could be an excellent strategy in patients suffering from mitral regurgitation caused by P2 prolapse when quadrangular resection cannot be performed. The main objective of the present study is to examine the medium to long-term outcomes (in terms of survival and plastic outcomes) of patients undergoing central edge-to-edge to treat posterior flap pathology (P2).

Conditions

• Degenerative Mitral Valve Disease
• Mitral Regurgitation

Interventions

Type	Name	Description
PROCEDURE	Central edge-to-edge	Suture of free margins of the mitral leaflets in central position to restore coaptation

Timeline

• Start date: 2019-10-05
• Primary completion: 2019-10-15
• Completion: 2019-10-15
• First posted: 2023-05-01
• Last updated: 2023-05-01

Locations

1 site across 1 country: Italy