NCT05836480

Immediate Suboptimal Result of Mitral Valve Repair: Late Implications in a Matched Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 141 (actual)
• Sponsor: Michele De Bonis · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Mitral valve regurgitation is a pathology affecting the left atrioventricular valve, conditioning the loss of the normal unidirectionality of the atrioventricular flow and therefore volumetric and pressure overload of the left heart chambers. In industrialized countries, the most common etiology of mitral regurgitation is degenerative mitral disease. Mitral valve repair surgery represents the gold standard for the treatment of severe degenerative mitral regurgitation. The expected optimal result would be the absence of residual post-procedural mitral regurgitation, even if it is not uncommon to obtain a valve with residual regurgitation of a mild degree. In some cases, for various reasons (technical difficulties, long aortic clamping time, advanced age, high pre-operative surgical risk), a suboptimal result is accepted, i.e. a post-procedural residual mitral regurgitation of even a moderate degree ( 0, 1+, or 2+/4+). The aim of the present study is to evaluate the late clinical and echocardiographic implications of suboptimal mitral valve repair with a paired-data cohort study

Conditions

• Mitral Regurgitation

Interventions

Type	Name	Description
PROCEDURE	mitral valve repair	conservative surgery to treat mitral regurgitation. A mitral valve plasty is performed according to the most appropriate technique

Timeline

• Start date: 2019-10-05
• Primary completion: 2019-10-15
• Completion: 2019-10-15
• First posted: 2023-05-01
• Last updated: 2023-05-01

Locations

1 site across 1 country: Italy